Advantages of Microbe-derived Enzyme Preparations

Though animal-based pancreatic enzymes are the well-accepted form of supplementation in certain individuals to address exocrine pancreatic insufficiency, oral supplementation with non-animal derived enzymes, such as microbe-based enzymes is associated with a number of inherent advantages:


Studies have demonstrated that microbe-derived enzymes like lipase are promising, as their activity is believed to be similar to porcine and bovine pancreatic enzymes


Data on the safety and efficacy of microbe-derived enzymes in malabsorption and lactose intolerance are encouraging


In comparison to animal-based enzyme preparations, microbe-based counterparts offer effective digestive support, which are believed to work synergistically with, or as an alternative to the former


Microbe-based enzymes are free of some of the inherent limitations of conventional pancreatic enzyme supplements


Microbe-derived enzymes provide a broad-spectrum of digestive enzymes, viz. protease, lipase, amylase, lactase, cellulase, etc


Microbe-derived enzymes may be used at a lower dosage and possess a broader pH range (i.e. 2–11) of activity compared to animal-based enzymes, which function in a limited alkaline pH range


This unusually high stability and activity throughout a wide range of pH conditions enables microbe-based enzymes function more consistently for a longer distance as they are transported through the digestive tract (i.e. in the stomach as well as the small intestine)


Animal-based enzymes work better at body temperature, while microbe-based counterparts are highly active at higher temperatures


Micro-organisms as a source of enzymes for nutritional supplements are inexpensive and provide abundant supply


Enzyme mixtures have a wider range of advantage than individual enzymes, according to Dr. Peter Streichhan, a world-renowned enzyme researcher